产品货号：
Z15981
中文名称：
DRP1/DNM1L抗体
英文名称：
Anti-DRP1/DNM1L Antibody (C-term)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DRP1/DNM1L Antibody (C-term) |
| 指标别名 | DLP1;DNM1L;DRP1;DRP1 (C-terminal) |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | DNM1L |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This DNM1L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 513-547 amino acids from the C-terminal region of human DNM1L. |
| 计算分子量 | 82kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Functions in mitochondrial and peroxisomal division.Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism.Through its function in mitochondrial division,ensures the survival of at least some types of postmitotic neurons,including Purkinje cells,by suppressing oxidative damage.Required for normal brain development,including that of cerebellum.Facilitates developmentally regulated apoptosis during neural tube formation.Required for a normal rate of cytochrome c release and caspase activation during apoptosis;this requirement may depend upon the cell type and the physiological apoptotic cues.Also required for mitochondrial fission during mitosis.Required for formation of endocytic vesicles.Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X (L) which stimulates its GTPase activity in synaptic vesicles;the function may require its recruitment by MFF to clathrin-containing vesicles.Required for programmed necrosis execution. |
| Uniprot ID | O00429 |
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